Global Serotonin-norepinephrine Reuptake Inhibitors Market Size, Share - Industry Trends and Forecast 2016 - 2024
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Serotonin-norepinephrine
Reuptake Inhibitors: Overview
Serotonin-norepinephrine
reuptake inhibitors (SNRIs) or dual - uptake inhibitors represent one
of the newest but important classes of antidepressants, which are
commonly prescribed for anxiety disorders and depression therapeutic
treatment. SNRIs were first launched in the international markets in
1993, when the U.S. FDA approved first of its kind Venlafaxine
(Effexor) as an antidepressant, which would help treat numerous
individuals suffering from varying anxiety disorders and/or
depression.
However,
SNRIs belong to that group of antidepressants, which are used as a
second line treatment regimen for depression in addition to another
antidepressants class called Selective Serotonin Reuptake Inhibitors
(SSRIs). SNRIs work by blocking the re-absorption of two
neurotransmitters in the brain, namely Norepinephrine and serotonin,
thus, increasing the level of these two neurotransmitters in the
nerve cells. This property of SNRIs helps elevate the mood of an
individual suffering from depression or any type of anxiety disorder.
No severe side effects have been observed to be associated with SNRIs
usage; however, a few common side effects, such as nausea, dry mouth,
excessive sweating and dizziness are generally associated with this
class of antidepressants.
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Serotonin-norepinephrine
Reuptake Inhibitors: Key Drivers
Some
of the major driving factors for the growth of this market include
rising prevalence of depression and anxiety disorders globally,
improved efficacy and reduced side effects of SNRIs available in the
global market and rapidly increasing geriatric population. According
to the WHO estimates, in 2012, more than 350 million people were
found to be affected by depression worldwide. Similarly, the Anxiety
and Depression Association of America (ADAA) estimated that, in 2012,
around 14.8 million people in the U.S. were suffering from depression
only.
Aged
individuals are more prone to several depression and anxiety
disorders; hence, high geriatric population in most of the developed
economies and increasing age of people in developing nations will
also contribute towards the growth of this market in future. Improved
efficacy along with the reduction in the side effects due to SNRIs
will further contribute towards the growth of this market. Some of
the major drugs from this class that are available in the global
market include Desvenlafaxine (Pristiq), Duloxetine (Cymbalta),
Levomilnacipran (Fetzima) and Venlafaxine (Effexor XR). However, the
market for SNRIs may face challenges in future due to recent
expirations of lot of SNRIs and a weak pipeline of drugs from this
class of antidepressants, which will cause the introduction of a
large number of generics in the global market.
Serotonin-norepinephrine
Reuptake Inhibitors: Region-wise Insight
Geographically,
North America holds the leading position in the SNRIs market followed
by Europe. Key factor responsible for their dominance in this market
is high prevalence of anxiety disorders and depression in these
regions, especially in the U.S. According to the World Health
Organization (WHO), in 2012, about 16 million adults aged 18 or above
suffered from major depressive disorders in the U.S. Thus, large
patient population suffering from depression and other disorders has
helped the antidepressants market to grow significantly in the
region. Moreover, the Centers for Disease Control and Prevention
(CDC) suggested that frequent episodes of major depression were the
leading cause of suicide and disability among the U.S. citizens aged
between 15 years and 44 years.
However,
emerging economies of Asia Pacific, Middle East, LATAM and Africa
regions would present huge opportunities for the growth of this
market in future. Key factors responsible for the growth of this
market in these regions include economic growth, increased disposable
income and enhanced affordability of branded formulations in these
regions. Moreover, a growing geriatric population more prone to
psychiatric disorders such as depression, clinical anxiety, bipolar
disorder and other psychological conditions along with the presence
of a large population base in the region would consequently raise the
uptake of SNRIs.
Some
of the major players operating in this market are Eli Lilly and
Company, Forest Laboratories, Inc. and Pfizer, Inc.
The
report offers a comprehensive evaluation of the market. It does so
via in-depth insights, understanding market evolution by tracking
historical developments, and analyzing the present scenario and
future projections based on optimistic and likely scenarios. Each
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study is a source of reliable data on:
Key
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Evolving
market trends and dynamics
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supply and demand scenarios
Quantifying
market opportunities through market sizing and market forecasting
Tracking
current trends/opportunities/challenges
Competitive
insights
Opportunity
mapping in terms of technological break throughs
The
regional analysis covers:
North
America (U.S. and Canada)
Latin
America (Mexico, Brazil, Peru, Chile, and others)
Western
Europe (Germany, U.K., France, Spain, Italy, Nordic countries,
Belgium, Netherlands, Luxembourg)
Eastern
Europe (Poland, Russia)
Asia
Pacific (China, India, Japan, ASEAN, Australia and New Zealand)
Middle
East and Africa (GCC, Southern Africa, North Africa)
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