Overview Of NASH Market 2026: Epidemiology, Etiology, Pathophysiology, Symptoms, Diagnosis And Current Management Strategies
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Analysis and Forecasts to 2026 provides information on pricing,
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About
NASH Market
First described in 1980,
nonalcoholic steatohepatitis (NASH) (ICD-10-CM = K75.81) is a
condition that develops as a subgroup of nonalcoholic fatty liver
disease (NAFLD) when excessive fat buildup is accompanied by liver
cell injury and inflammation. NAFLD is defined by excessive fat
accumulation in the form of triglycerides (steatosis) in the liver.
Progression of this condition to NASH dramatically increases the risk
of cirrhosis, liver failure, and hepatocellular carcinoma, and it is
therefore a potentially fatal condition .
GlobalData estimates the 2016
sales for the NASH market at approximately $618m across the 7MM,
encompassing the US, the five major European Union countries (5EU:
France, Germany, Italy, Spain, and UK), and Japan. Over the course of
the 10-year forecast period, the NASH market will grow at a Compound
Annual Growth Rate (CAGR) of 45.0% across the 7MM. The US and
Japanese markets are both anticipated to grow significantly,
recording CAGRs of 48.1% and 50.7%, respectively, while the 5EU will
record a CAGR of 30.6%. At the end of 2026, the US will account for
around 88% of global sales, while the 5EU and Japan will account for
around 10% and 2% of sales, respectively. The higher sales numbers
for the US can be attributed to the higher prices of pharmaceuticals
and the greater diagnosed prevalence of NASH in the region, as well
as the launch of more pipeline agents in this region.
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Key Questions Answered
How will the NASH market landscape
in the 7MM (US, France, Germany, Italy, Spain, UK and Japan) change
from 2016–2026?
What are the most promising
late-stage pipeline drugs in NASH?
How do the clinical and commercial
attributes of late-stage pipeline therapies compare with one another,
and against existing treatment options?
What are the greatest unmet needs
in NASH? Will the pipeline drugs fulfil these needs of the market?
What are the biggest opportunities
in the NASH landscape?
Scope
Overview of NASH, including
epidemiology, etiology, pathophysiology, symptoms, diagnosis, and
current management strategies.
Topline NASH market revenue from
2016–2026. Annual cost of therapy (ACOT) and major pipeline product
sales in this forecast period are included.
Key topics covered include current
treatment options, unmet needs and opportunities, and the drivers and
barriers affecting NASH therapeutics sales in the 7MM.
Pipeline analysis: comprehensive
data split across different phases, emerging novel trends under
development, synopses of innovative early-stage projects, and
detailed analysis of late-stage pipeline products.
Analysis of the current and future
market competition in the global NASH therapeutics market. Insightful
review of the key industry drivers, restraints and challenges. Each
trend is independently researched to provide qualitative analysis of
its implications.
Reasons to buy
The report will enable you to:
Develop and design your
in-licensing and out-licensing strategies through a review of
pipeline products and technologies, and by identifying the companies
with the most robust pipeline.
Develop business strategies by
understanding the trends shaping and driving the global NASH
therapeutics market.
Drive revenues by understanding
the key trends, innovative products and technologies, market
segments, and companies likely to impact the NASH therapeutics market
in the future.
Formulate effective sales and
marketing strategies by understanding the competitive landscape and
by analyzing the performance of various competitors.
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Identify emerging players with
potentially strong product portfolios and create effective
counter-strategies to gain a competitive advantage.
Organize your sales and marketing
efforts by identifying the market categories and segments that
present maximum opportunities for consolidations, investments, and
strategic partnerships.
Companies mentioned
Gilead Sciences
Intercept Pharmaceuticals
Genfit SA
Allergan Plc
Galectin Therapeutics
Galmed Pharmaceuticals
Inventiva Pharma
Novo Nordisk
Conatus Pharmaceuticals
Novartis
Immuron Limited
Cirius Therapeutics
Table of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Executive Summary
2.1 Mid-Forecast Surge in Sales
for NASH
2.2 Manufacturers Are Employing
Strategies to Improve Diagnostics while Advancing Drug Development
2.3 Vast Unmet Needs Exist in the
NASH Market
2.4 Opportunities Abound for Tools
that Support Accurate Diagnosis
2.5 Launches of Novel Pipeline
Products Will Revolutionize the NASH Treatment Landscape
2.6 What Do the Physicians Think?
3 Introduction
3.1 Catalyst
3.2 Related Reports
4 Disease Overview
4.1 Etiology and Pathophysiology
4.1.1 Etiology
4.1.2 Pathophysiology
4.2 Disease Staging
4.3 Symptoms
5 Epidemiology
5.1 Risk Factors and Comorbidities
5.2 Global Trends
5.2.1 US
5.2.2 5EU
5.2.3 Japan
5.3 Forecast Methodology
5.3.1 Sources Used Tables
5.3.2 Forecast Assumptions and
Methods
5.3.3 Sources Not Used
5.4 Epidemiological Forecast for
NASH (2016–2026)
5.4.1 Total Prevalent Cases of
NASH
5.4.2 Age-Specific Total Prevalent
Cases of NASH
5.4.3 Sex-Specific Total Prevalent
Cases of NASH
5.4.4 Age-Standardized Prevalence
of NASH
5.4.5 Diagnosed Prevalent Cases of
NASH
5.4.6 Diagnosed Prevalent Cases of
NASH by Comorbid Disorder
5.5 Discussion
5.5.1 Epidemiological Forecast
Insight
5.5.2 Limitations of the Analysis
5.5.3 Strengths of the Analysis
6 Current Treatment Options
6.1 Overview
6.2 Diagnosis
6.3 Treatment Guidelines and
Leading Prescribed Drugs
6.4 Product Profiles
6.4.1 Vitamin E
6.4.2 Pentoxifylline
6.4.3 Pioglitazone
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